A NOVEL NANOEMULSION-BASED METHOD TO PRODUCE ULTRASMALL, WATER-DISPERSIBLE NANOPARTICLES FROM CHITOSAN, SURFACE MODIFIED WITH CELL-PENETRATING PEPTIDE FOR ORAL DELIVERY OF PROTEINS AND PEPTIDES

A novel nanoemulsion-based method to produce ultrasmall, water-dispersible nanoparticles from chitosan, surface modified with cell-penetrating peptide for oral delivery of proteins and peptides

Ghullam Reza Barbari,1 Farid Abedin Dorkoosh,1 Mohsen Amini,2 Mohammad Sharifzadeh,3 Fateme Atyabi,1 Saeed Balalaie,4 Niyousha Rafiee Tehrani,5 Morteza Rafiee Tehrani1 1Department of Pharmaceutics, 2Department of Medicinal Chemistry, 3Department of Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, 4Department of Chemistry, Kh

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Supervised learning and model analysis with compositional data.

Supervised learning, such as regression and classification, is an essential tool for analyzing modern high-throughput sequencing data, for example in microbiome research.However, due to the compositionality and sparsity, existing techniques are often inadequate.Either they rely on extensions of the linear log-contrast model (which adjust for compos

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School Craft in Memories of Three Generations

Throughout Finnish elementary school 150-year-history, school craft has served the teaching needs Ball - Shoes Turf - Mens of societal, educational, new craft techniques, tools and materials in every school.This article studies memories associated with school craft throughout three consecutive generations.The focus is particularly on what kind of m

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Estimation precision of degree of polarization in the presence of signal-dependent and additive Poisson noises

We address precision of estimation of the degree of polarization (DOP) from the orthogonal state contrast image (OSCI) in the presence of both signal-dependent Poisson noise due Lip Gloss to useful signal, and additive Poisson noise due to dark current and / or background light.We determine the Cramer Rao Lower Bound and deduce from it figures of m

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